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It is reported that treatment of CRC cells with luteolin, a naturally occurring flavonoid which is an agonist of PPAR, increased mRNA and protein expression of OCTN2 in a time- and dose-dependent manner, enhancing the intracellular accumulation of oxaliplatin (Qu et al., 2014)

do not assume a standard concentration

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studied the effects of the small-molecule IDO inhibitor INCB024360 treatment in 52 cancer patients

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